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Dr Mathur Ranjana

MBBS, M Med(Ophth), FRCS(Ed)

Senior Consultant

Singapore National Eye Centre

Specialty: Medical Retina, Cataract ＆ Comprehensive Ophthalmology

Clinical Interest: Medical Retina, Cataract ＆ Comprehensive Ophthalmology

Conditions Treated by this Doctor:
Age-related Macular Degeneration, Cataract Surgery, Central Serous Chorioretinopathy, Diabetic Retinopathy, Retinal Vascular Disorders.

Clinical Appointments

Senior Consultant Medical Retina Department Singapore National Eye Centre
Senior Consultant Cataract ＆ Comprehensive Ophthalmology Department Singapore National Eye Centre

Academic Appointments

Clinical Asst Professor SingHealth Duke-NUS Ophthalmology ＆ Visual Sciences Academic Clinical Programme

Profile

Dr Ranjana Mathur is a Senior Consultant in the Medical Retina Department in Singapore National Eye Centre and a Clinical Assistant Professor with Duke-NUS Medical School. Following completion of her Master in Ophthalmology and Diplomat of National Board degree in India, she obtained the degree of Master of Medicine (Ophthalmology) from the National University of Singapore and Fellowship of Royal College of Surgeons, Edinburgh in 1998. She joined Singapore National Eye centre faculty as Associate Consultant in Vitreo-Retinal service after completion of her specialist training and medical retina fellowship in 2004.

In addition to performing cataract surgeries, her sub-specialty interest includes managing age-related macular degeneration (AMD), diabetic retinopathy, retinal vascular pathology; three of the most common blinding retinal conditions. She has special interest in inherited retinal conditions such as retinitis pigmentosa, Stargardt macular dystrophy and role of electrophysiology in diagnosing complex retinal and optic nerve conditions. She currently holds position of Adjunct Clinical Scientist at Singapore Eye Research Institute.

She has designed and implemented new model of primary eye care at SNEC (PEC). She is Principal Investigator for MOH HSDP grant which is looking at National community Eye Care clinic, in collaboration with other Singapore restructured eye hospitals. She is the first SNEC Institutional Risk Officer and in her role of IRO she has conceptualized and implemented enterprise risk management framework by engaging various clinical departments, to achieve safe clinical processes for better patient safety.

She has been awarded SingHealth Service Quality Award twice (Gold and Silver) for her role as a clinician and Best Teacher Award as an educator. And has author >50 peer-reviewed international papers.

Education

FRCS(Ed) (1998)
M Med(Ophth) (1998)
MBBS

Professional Appointments and Committee Memberships

Co-opted COPAP-I Committee Member, Ministry of Health (2017)
Institutional Risk Officer, SingHealth Procedural Safety Workgroup (2013 - present)
Medical Panel, Medical Assistance Fund (MAF), Singapore National Eye Centre (2013 - present)
Medical Specialist Panel of Work Injury Compensation Medical Board, Ministry of Manpower (2012 - present)
Institutional Risk Officer (IRO), Singapore National Eye Centre (2011 - present)
Member, Quality Assurance Committee, Singapore National Eye Centre (2011 - present)
Proceedings Editorial Committee, Singapore General Hospital (2009 - 2011)

Awards

Best Teacher Award, SingHeath Residency (2017)
Best Teacher Award, Singapore National Eye Centre (2016)
Gold Award, Singapore Health Quality Service Award, SingHealth (2013)
Silver Award, Singapore Health Quality Service Award, SingHealth (2007)

Research Interests

Publications

Fan Q, Cheung CMG, Chen LJ, Yamashiro K, Ahn J, Laude A, Mathur R, Mun CC, Yeo IY, Lim TH, Teo YY, Khor CC, Park KH, Yoshimura N, Pang CP, Wong TY, Cheng CY. Shared genetic variants for polypoidal choroidal vasculopathy and typical neovascular age-related macular degeneration in East Asians. J Hum Genet. 2017 Dec;62(12):1049-1055
Teo KYC, Yanagi Y, Lee SY, Yeo IYS, Tan GSW, Mathur R, Chan CM, Wong TY, Cheung CMG. Comparison of optical coherence tomography angiographic changes after anti-vascular endothelial growth factor therapy alone or in combination with photodynamic therapy in polypoidal choroidal vasculopathy. Retina. 2017 Aug 1
Loh HP, de Korne DF, Chee SP, Mathur R. Reducing wrong intraocular lens implants in cataract surgery. Int J Health Care Qual Assur. 2017 Jul 10;30(6):492-505. doi: 10.1108/IJHCQA-06-2016-0095. PubMed PMID: 28714828
Yanagi Y, Ting DSW, Ng WY, Lee SY, Mathur R, Chan CM, Yeo I, Wong TY, Cheung GCM. Choroidal vascular hyperpermeability as a predictor of treatment response for polypoidal choroidal vasculopathy. Retina. 2017 Jul 12
Yanagi Y, Mohla A, Lee WK, Lee SY, Mathur R, Chan CM, Yeo I, Wong TY, Cheung CMG. Prevalence and risk factors for nonexudative neovascularization in fellow eyes of patients with unilateral age-related macular degeneration and polypoidal choroidal vasculopathy. Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3488-3495
Fenwick EK, Cheung GCM, Tl Gan A, Tan G, Lee SY, Wong D, Yeo I, Mathur R, Wong TY, Lamoureux EL. Change in vision-related quality of life and influencing factors in Asians receiving treatment for neovascular age-related macular degeneration. Br J Ophthalmol. 2017 Jun 28. pii: bjophthalmol-2017-310532
Wong CW, Ng SR, Cheung CM, Wong TY, Mathur R. Zika-related maculopathy. Retin Cases Brief Rep. 2017 Feb 17
Cheung CM, Laude A, Yeo I, Tan SP, Fan Q, Mathur R, Lee SY, Chan CM, Tan G,Lim TH, Cheng CY, Wong TY. Systemic, ocular and genetic risk factors for age-related macular degeneration and polypoidal choroidal vasculopathy in Singaporeans. Sci Rep. 2017 Jan 25;7:41386
Cheung CMG, Yanagi Y, Mohla A, Lee SY, Mathur R, Chan CM, Yeo I, Wong TY. Characterization and differentiation of polypoidal choroidal vasculopathy using swept source optical coherence tomography angiography. Retina. 2017 Aug;37(8):1464-1474
Singh MS, Broadgate S, Mathur R, Holt R, Halford S, MacLaren RE. Hypotrichosis and juvenile macular dystrophy caused by CDH3 mutation: A candidate disease for retinal gene therapy. Sci Rep. 2016 May 9;6:23674
Ting DS, Ng WY, Ng SR, Tan SP, Yeo IY, Mathur R, Chan CM, Tan AC, Tan GS,Wong TY, Cheung CM. Choroidal thickness changes in age-related macular degeneration and polypoidal choroidal vasculopathy: A 12-month prospective study. Am J Ophthalmol. 2016 Apr;164:128-36
Lim FP, Wong CW, Loh BK, Chan CM, Yeo I, Lee SY, Mathur R, Wong D, Wong TY,Cheung CM. Prevalence and clinical correlates of focal choroidal excavation in eyes with age-related macular degeneration, polypoidal choroidal vasculopathy and central serous chorioretinopathy. Br J Ophthalmol. 2016 Jul;100(7):918-923
Lim LS, Ng WY, Mathur R, Wong D, Wong EY, Yeo I, Cheung CM, Lee SY, Wong TY, Papakostas TD, Kim LA. Conversion to aflibercept for diabetic macular edema unresponsive to ranibizumab or bevacizumab. Clin Ophthalmol. 2015 Sep 16;9:1715-8
Cheung CM, Laude A, Wong W, Mathur R, Chan CM, Wong E, Wong D, Wong TY, Lim TH. Improved specificity of polypoidal choroidal vasculopathy diagnosis using a modified Everest criteria. Retina. 2015 Jul;35(7):1375-80
Wong MH, Cheung GC, Chee SP, Mathur R. Exudative detachment as a masquerader in hypoalbuminaemic patients. Clin Kidney J. 2014 Aug;7(4):406-10
Wong CW, Cheung CM, Mathur R, Li X, Chan CM, Yeo I, Wong E, Lee SY, Wong D,Wong TY. Three-year results of polypoidal choroidal vasculopathy treated with photodynamic therapy: Retrospective Study and Systematic Review. Retina. 2015 Aug;35(8):1577-93
Cheng CY, Yamashiro K, Chen LJ, Ahn J, Huang L, Huang L, Cheung CM, Miyake M, Cackett PD, Yeo IY, Laude A, Mathur R, Pang J, Sim KS, Koh AH, Chen P, Lee SY,Wong D, Chan CM, Loh BK, Sun Y, Davila S, Nakata I, Nakanishi H, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Matsuda F, Mori K, Yoneya S, Sakurada Y, Iijima H, Iida T, Honda S, Lai TY, Tam PO, Chen H, Tang S, Ding X, Wen F, Lu F, Zhang X, Shi Y, Zhao P, Zhao B, Sang J, Gong B, Dorajoo R, Yuan JM, Koh WP, van Dam RM,Friedlander Y, Lin Y, Hibberd ML, Foo JN, Wang N, Wong CH, Tan GS, Park SJ,Bhargava M, Gopal L, Naing T, Liao J, Ong PG, Mitchell P, Zhou P, Xie X, Liang J,Mei J, Jin X, Saw SM, Ozaki M, Mizoguchi T, Kurimoto Y, Woo SJ, Chung H, Yu HG,Shin JY, Park DH, Kim IT, Chang W, Sagong M, Lee SJ, Kim HW, Lee JE, Li Y, Liu J,Teo YY, Heng CK, Lim TH, Yang SK, Song K, Vithana EN, Aung T, Bei JX, Zeng YX,Tai ES, Li XX, Yang Z, Park KH, Pang CP, Yoshimura N, Wong TY, Khor CC. New loci and coding variants confer risk for age-related macular degeneration in East Asians. Nat Commun. 2015 Jan 28;6:6063
Cheung CM, Yang E, Lee WK, Lee GK, Mathur R, Cheng J, Wong D, Wong TY, Lai TY. The natural history of polypoidal choroidal vasculopathy: a multi-centre series of untreated Asian patients. Graefes Arch Clin Exp Ophthalmol. 2015 Dec;253(12):2075-85
Ng WY, Tan GS, Ong PG, Cheng CY, Cheung CY, Wong DW, Mathur R, Chow KY, Wong TY, Cheung GC. Incidence of myocardial infarction, stroke, and death in patients with age-related macular degeneration treated with intravitreal anti-vascular endothelial growth factor therapy. Am J Ophthalmol. 2015 Mar;159(3):557-64.e1
Wong CW, Wong D, Mathur R. Spectral domain optical coherence tomography imaging in optic disk pit associated with outer retinal dehiscence. Clin Ophthalmol. 2014 Oct 17;8:2125-8