Grants FY17-18

NMRC

• “Deep Phenotyping and Genetic Landscaping of Primary Open Angle Glaucoma”.
  A/Prof Cheng Ching Yu; S$1,750,000.00

• “Novel Multimodal Imaging in Moderate Diabetic Retinopathy to Predict Vision-Threatening Stages of Retinopathy”.
  Dr Gavin Tan; S$375,000.00

• “Optimization of Core Platform Technologies for Ocular Research (INCEPTOR)”.
  Prof Aung Tin; S$16,000.000.00

• “Singapore Imaging Eye Network SIENA”.
  Prof Leopold Schmetterer; S$3,823,708.00

• “Liposomes as a Drug Delivery Mechanism for the Treatment of Proliferative Vitreoretinopathy”.
  Dr Wong Chee Wai; S$209,850.00

• “Visually-disabling pathologic myopia in the SEED and SCORM high myopia cohorts: Longitudinal changes, novel biomarkers and impact on health-related quality of life”.
  Prof Saw Seang Mei; S$1,190,025.78

• “DYNAMO: Diabetes Study on Nephropathy and other microvascular complications. Theme 3: Retinal microvasculature as a “window” to study mechanisms and pathways in DN”.
  Prof Wong Tien Yin; S$4,999,850.00

• “The applications of Terahertz scanning system on corneas”.
  Dr Liu Yu Chi; S$378,000.00

• “Quantification of blood flow based on OCT-angiography”.
  Prof Leopold Schmetterer; S$850,000.00

• “Role of polarized macrophages and long noncoding RNAs in the pathogenesis of polypoidal choroidal vasculopathy”.
  A/Prof Yasuo Yanagi; S$674,966.00

• “Translational Program in Ocular Surface and Dry Eye”.
  A/Prof Louis Tong; S$1,749,909.00

• “Harnessing LOXL1 as a therapeutic candidate for exfoliation syndrome and exfoliation glaucoma”
  Prof Aung Tin; S$1,445,238.15

• “Safety and Efficacy of Tissue Engineered Endothelial Keratoplasty (TE-EK)”
  A/Prof Jodhbir Mehta; S$1,249,975.00

A*Star/ Duke-NUS/ MOH/ Others

• “Effect of aging of the innate immune system on intracellular system network”.
  A/Prof Yasuo Yanagi; S$250,000.00

• “SERI Santen Strategic Collaboration and Joint Ophthalmic Research Laboratory”.
  Prof Aung Tin; S$13,650,000.00

• “The Molecular Therapeutics Programme”.
  A/Prof Jodhbir Mehta; S$3,448,229.00

• “Investigating the effect of blood pressure and intraocular pressure modulation on the neurovascular unit of the eye”.
  Dr Rachel Chong; S$171,307.00

• “Innovations in High Resolution Corneal Imaging for the Clinic”.
  Prof Leopold Schmetterer; S$100,000.00

• “Developing a Novel Retinopexy Device to Improve Visual Outcome of Retinal Detachment Surgery”.
  Dr Cheung Ning; S$50,000.00

• “A simultaneous extractor-injector device”.
  Dr Marcus Ang; S$30,000.00

• “A Handheld Pupillometer for a Fast and Cost-effective Ocular Disease Screening”.
  Prof Dan Milea; S$208,290.00

• “A Longitudinal Study on the Structural-functional Correlations of Perifoveal Capillary Network Integrity in Diabetes Using Optical Coherence Tomography Angiography”.
  Dr Andrew Tsai; S$25,000.00

• “A polymer product and preparation thereof”.
  A/Prof Lakshminarayanan Rajamani; S$40,000.00

• “Identification of a dental pulp stem cell (DPSC) sub population as a novel source for retinal stem cell transplantation”.
  Dr Shweta Singhal; S$20,000.00

SingHealth

• “Replacement of OAHFA in human tear using an over-the-counter eyedrop medical device to prevent dry eye”.
  Dr Hou Aihua; S$100,000.00

• “Developing a Predictive Model for Non-Adherence to Recommended Ophthalmic Referrals in Persons with Diabetes (PM-OR)”.
  Dr Ryan Man; S$149,829.00
  “Storage and transport of constructs for corneal endothelial transplantation”.
  Dr Matthew Lovatt; S$149,892.00

• “Targeting Lipid A for Antibiotic Synergy”.
  Dr Koh Jun Jie; S$50,000.00

Commercial

• “A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients with Open-Angle Glaucoma or Ocular Hypertension”.
  A/Prof Shamira Perera; S$139,066.33

• “A Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 Delivered By Single or Multi-Dose Intravitreal Injection(s) to Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)”
  A/Prof Sharon Tow; S$113,473.39

• “A Phase II, Randomized, Double-Masked, Placebo-Controlled, Parallel-Group Study Assessing the Efficacy and Safety of DE-127 Ophthalmic Solution 0.0025%, 0.005% and 0.01% Compared with Placebo in Subjects with mild or moderate Myopia”.
  A/Prof Audrey Chia; S$700,566.29

• “Efficacy study of CMP molecules in rat model”.
  Dr Amutha Barathi Veluchamy; S$58,807.31

• “Drug safety evaluation of IBI302 and IBI304 from Biologics, through intra-vitreal injection, in NZW rabbit eyes (12 New Zealand White)”.
  Dr Yong Li; S$31,909.54

• “Drug efficacy evaluation of IBI302 and IBI304 from Biologics, through intra-vitreal injection, in 12 PRNV rabbits”.
  Dr Yong Li; S$70,189.86