Profile
Prof Schmetterer is head of Ocular Imaging and Scientific Director at SERI. His interests span a wide range of imaging from development of novel technology towards applications in preclinical research and clinics. Prof Schmetterer is also interested in clinical trials and is involved in many studies in retina, glaucoma, cornea and dry eye.
He has published more than 390 peer reviewed publications, was invited for more than 200 lectures; including more than 15 key note lectures and been awarded more than 30 million Euro in research grant funding. He is a member of the Editorial Boards of Progress in Retinal and Eye Research, Scientific Reports, Acta Ophthalmologica, Journal of Ocular Pharmacology and Therapeutics, Current Eye Research and 5 other journals.
Professional Appointments and Committee Memberships
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Professor, School of Chemical & Biomedical Engineering, Nanyang Technological University
- Professor (Honorary), Department of Ophthalmology, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
- Professorship in Vienna on hold (3 years) (2016 - 2019)
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Awards
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Gold Fellow, The Association for Research in Vision and Ophthalmology (ARVO) (2019)
- Honorary degree, Technical University, Bucharest (2019)
- Gold Medal, Acta Ophthalmoologica (2017)
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Honorary degree, Carol Davila University, Bucharest (2016)
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Hans Goldmann Medal, Switzerland (2015)
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International Bach Lecture, Leipzig (2014)
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Silver Fellow, The Association for Research in Vision and Ophthalmology (ARVO) (2014)
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Visionary of the Quarter, European Vision Institute (2011)
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First prize, International MSD Award (2002)
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Austrian Höchst Award (1998)
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Research Studies
- Multimodal imaging photoacoustic (2019 – present)
- Application of ultrahigh resolution OCT imaging (2019 – present)
- Quantitative Doppler OCT and OCT angiography imaging (2019 – present)
- In vivo functional OCT imaging (2019 – present)
- Imaging and drug delivery via contact lenses(2019 – present)
- Multimodal 2-photon imaging (2019 – present)
- Development of a polarization-sensitive optical coherence tomography (PS-OCT) system for characterization of scleral biomechanical properties (2019 – present)
- Assessment of chamber angle using hyperparallel OCT (2018 – present)
- Innovations in High Resolution Corneal Imaging for the Clinic (2017 – present)
- Visualization of aqueous humor outflow structures using ultra-high resolution OCT (2017 – present)
- Measurement of pre-corneal tear film thickness using ultra-high resolution OCT (2017 – present)
• Modelling of retinal blood flow based on retinal fundus photography (2017 – present)
• Visualization of corneal endothelial cells using ultra-high resolution OCT (2017 – present)
• OCT elastography for the quantification of biomechanical tissue properties (2017 – present)
• Quantification of blood flow based on OCT angiography (2016 – present)
• Modelling the pressure/flow relationship in patients with glaucoma (2016 – present)
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Publications
- Stable complex conjugate artifact removal in OCT using circularly polarized light as reference. Liu X, Ke M, Yao X, Chua J, Schmetterer L, Tan B. Opt Lett. 2020 Jul 15;45(14):3977-3980.
- Longitudinal Structural and Microvascular Observation in RCS Rat Eyes Using Optical Coherence Tomography Angiography. Tan B, Barathi VA, Lin E, Ho C, Gan A, Yao X, Chan A, Wong DWK, Chua J, Tan GS, Schmetterer L. Invest Ophthalmol Vis Sci. 2020 Jun 3;61(6):54.
- Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy. Chua J, Sim R, Tan B, Wong D, Yao X, Liu X, Ting DSW, Schmidl D, Ang M, Garhöfer G, Schmetterer L. J Clin Med. 2020 Jun 3;9(6):1723.
- Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope. Yao X, Ke M, Ho Y, Lin E, Wong DWK, Tan B, Schmetterer L, Chua J. Br J Ophthalmol. 2020 May 27:bjophthalmol-2020-316111.
- Factors affecting the diagnostic performance of circumpapillary retinal nerve fibre layer measurement in glaucoma. Wong D, Chua J, Baskaran M, Tan B, Yao X, Chan S, Tham YC, Chong R, Aung T, Lamoureux EL, Vithana EN, Cheng CY, Schmetterer L. Br J Ophthalmol. 2020 May 5:bjophthalmol-2020-315985.
- Anatomical and functional changes in the retina in patients with Alzheimer's disease and mild cognitive impairment. Szegedi S, Dal-Bianco P, Stögmann E, Traub-Weidinger T, Rainer M, Masching A, Schmidl D, Werkmeister RM, Chua J, Schmetterer L, Garhöfer G. Acta Ophthalmol. 2020 Mar 25.
- One year structural and functional glaucoma progression after trabeculectomy. Chua J, Kadziauskienė A, Wong D, Ašoklis R, Lesinskas E, Quang ND, Chong R, Tan B, Girard MJA, Mari JM, Crowston JG, Aung T, Schmetterer L. Sci Rep. 2020 Feb 18;10(1):2808.
- The Effect of Orally Administered Dronabinol on Optic Nerve Head Blood Flow in Healthy Subjects-A Randomized Clinical Trial. Hommer N, Kallab M, Szegedi S, Puchner S, Stjepanek K, Bauer M, Werkmeister RM, Schmetterer L, Abensperg-Traun M, Garhöfer G, Schmidl D. Clin Pharmacol Ther. 2020 Jul;108(1):155-161.
- Quantitative Microvascular Analysis With Wide-Field Optical Coherence Tomography Angiography in Eyes With Diabetic Retinopathy. Tan B, Chua J, Lin E, Cheng J, Gan A, Yao X, Wong DWK, Sabanayagam C, Wong D, Chan CM, Wong TY, Schmetterer L, Tan GS. JAMA Netw Open. 2020 Jan 3;3(1):e1919469.
- Age-related changes of individual macular retinal layers among Asians. Chua J, Tham YC, Tan B, Devarajan K, Schwarzhans F, Gan A, Wong D, Cheung CY, Majithia S, Thakur S, Fischer G, Vass C, Cheng CY, Schmetterer L. Sci Rep. 2019 Dec 30;9(1):20352.
- In vivo corneal endothelium imaging using ultrahigh resolution OCT. Yao X, Devarajan K, Werkmeister RM, Dos Santos VA, Ang M, Kuo A, Wong DWK, Chua J, Tan B, Barathi VA, Schmetterer L. Biomed Opt Express. 2019 Oct 11;10(11):5675-5686.
- Comparison of a commercial spectral-domain OCT and swept-source OCT based on an angiography scan for measuring circumpapillary retinal nerve fibre layer thickness. Tan B, Chua J, Harish T, Lau A, Gan ATL, Tan YL, Wong DWK, Chong RS, Ang M, Husain R, Schmetterer L. Br J Ophthalmol. 2020 Jul;104(7):974-979.
- Age-Related Decline of Retinal Oxygen Extraction in Healthy Subjects. Bata AM, Fondi K, Szegedi S, Aschinger GC, Hommer A, Schmidl D, Chua J, Werkmeister RM, Garhöfer G, Schmetterer L. Invest Ophthalmol Vis Sci. 2019 Jul 1;60(8):3162-3169.
- Nitric oxide: a drug target for glaucoma revisited. Garhöfer G, Schmetterer L. Drug Discov Today. 2019 Aug;24(8):1614-1620.
- Compensation of retinal nerve fibre layer thickness as assessed using optical coherence tomography based on anatomical confounders. Chua J, Schwarzhans F, Nguyen DQ, Tham YC, Sia JT, Lim C, Mathijia S, Cheung C, Tin A, Fischer G, Cheng CY, Vass C, Schmetterer L. Br J Ophthalmol. 2020 Feb;104(2):282-290.
- Deep learning in ophthalmology: The technical and clinical considerations. Ting DSW, Peng L, Varadarajan AV, Keane PA, Burlina PM, Chiang MF, Schmetterer L, Pasquale LR, Bressler NM, Webster DR, Abramoff M, Wong TY. Prog Retin Eye Res. 2019 Sep;72:100759
- CorneaNet: fast segmentation of cornea OCT scans of healthy and keratoconic eyes using deep learning. Dos Santos VA, Schmetterer L, Stegmann H, Pfister M, Messner A, Schmidinger G, Garhofer G, Werkmeister RM. Biomed Opt Express. 2019 Jan 17;10(2):622-641.
- Quantitative analysis of choriocapillaris in non-human primates using swept-source optical coherence tomography angiography (SS-OCTA). Tan B, Chua J, Barathi VA, Baskaran M, Chan A, Lin E, Ang M, Klose G, Schmetterer L. Biomed Opt Express. 2018 Dec 21;10(1):356-371.
- Long-Term Shape, Curvature, and Depth Changes of the Lamina Cribrosa after Trabeculectomy. Kadziauskienė A, Jašinskienė E, Ašoklis R, Lesinskas E, Rekašius T, Chua J, Cheng CY, Mari JM, Girard MJA, Schmetterer L. Ophthalmology. 2018 Nov;125(11):1729-1740.
- Anterior segment optical coherence tomography. Ang M, Baskaran M, Werkmeister RM, Chua J, Schmidl D, Aranha Dos Santos V, Garhöfer G, Mehta JS, Schmetterer L. Prog Retin Eye Res. 2018 Sep;66:132-156.
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