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Clin Assoc Prof Chan Choi Mun

MBBS, MRCSEd, M Med(Ophth), FRCS(Ed), FAMS

Senior Consultant

Singapore National Eye Centre

Specialty: Medical Retina, Cataract ＆ Comprehensive Ophthalmology

Clinical Interest: Medical Retina, Cataract ＆ Comprehensive Ophthalmology

Conditions Treated by this Doctor:
Age-related Macular Degeneration, Cataract Surgery, Diabetic Retinopathy.

Clinical Appointments

Institution Lead (SNEC) SingHealth Duke-NUS Genomic Medicine Centre
Senior Consultant Medical Retina Department Singapore National Eye Centre
Senior Consultant Cataract ＆ Comprehensive Ophthalmology Department Singapore National Eye Centre
Clinical Director Visual Electrodiagnostic Service Singapore National Eye Centre

Academic Appointments

Clinical Associate Professor SingHealth Duke-NUS Ophthalmology ＆ Visual Sciences Academic Clinical Programme

Profile

Clinical Associate Professor Chan is a Senior Consultant with the Singapore National Eye Centre, having been with the Centre since 2000. She sees and performs surgeries on patients with general eye complaints such as cataracts as well as patients with retinal problems, including those with age-related macular degeneration; diabetic retinopathy and maculopathy; central and branch retinal vein occlusions; and inherited retinal dystrophies.

Clinical Associate Professor Chan obtained her basic medical degree from the University of Sydney in 1998 while on both the Equity and Merit Scholarship, as well as the Wesley College Scholarship. She completed her post-graduate training in Ophthalmology and obtained her Masters of Medicine from the National University of Singapore in 2004, and her Fellowship of the Royal College of Surgeons (Ophthalmology) from Edinburgh in 2007. Subsequently, she achieved Specialist Accreditation with the Ministry of Health in Singapore and was admitted as a Fellow of the Academy of Medicine of Singapore (FAMS). In 2008, Clinical Associate Professor Chan completed her fellowship in Medical Retina, specialising in the management of age-related macular degeneration; diabetic retinopathy and maculopathy; as well as central and branch retinal vein occlusions. In 2014, she completed a fellowship in inherited retinal dystrophies at the Moorfields Eye Hospital in London, UK while on the HMDP award from the Ministry of Health of Singapore.

Clinical Associate Professor Chan practices at the Singapore National Eye Centre and SNEC Branch at Bedok Clinic. Besides her clinical practice, Clinical Associate Professor Chan is also a Clinical Associate Professor at the Duke-NUS Medical School as well as Clinical Senior Lecturer with the Yong Loo Lin School of Medicine at the National University of Singapore, teaching junior doctors and medical students. She also organises and gives public talks on ophthalmological problems and their management.

Clinical Associate Professor Chan is currently involved in research in collaboration with the Singapore Eye Research Institute. She is a principal investigator on a NMRC grant researching the proteomics of tears in anterior segment disorder. She also is a sub-investigator on numerous trials researching the safety and efficacy of intravitreal medications in the treatment of age-related macular degenerations and retinal vein occlusions; as well as phenotyping of age-related macular degeneration.

In addition, Clinical Associate Professor Chan takes pride in providing personalised service to her patients and was awarded a Gold Award in the Singapore Health Quality Service Award 2016 as recognition for her efforts.

Education

FAMS (2007)
FRCS(Ed) (2007)
M Med(Ophth) (2004)
MRCSEd (2004)
MBBS (1998)

Professional Appointments and Committee Memberships

Senior Clinical Lecturer, Yong Loo Lin School of Medicine, National University of Singapore
Member, Infection Control Committee, Singapore National Eye Centre (2015-2018)
Clinical Physician Faculty Member, SingHealth Family Medicine Residency

Awards

Gold Award, Singapore Health Quality Service Award, SingHealth (2016)

Research Interests

Publications

Shared genetic variants for polypoidal choroidal vasculopathy and typical neovascular age-related macular degeneration in East Asians. Fan Q, Cheung CMG, Chen LJ, Yamashiro K, Ahn J, Laude A, Mathur R, Mun CC, Yeo IY, Lim TH, Teo YY, Khor CC, Park KH, Yoshimura N, Pang CP, Wong TY, Cheng CY. J Hum Genet. 2017 Dec;62(12):1049-1055. doi: 10.1038/jhg.2017.83. Epub 2017 Aug 24
Choroidal remodeling in age-related macular degeneration and polypoidal choroidal vasculopathy: A 12-month Prospective Study. Ting DSW, Yanagi Y, Agrawal R, Teo HY, Seen S, Yeo IYS, Mathur R, Chan CM, Lee SY, Wong EYM, Wong D, Wong TY, Cheung GCM. Sci Rep. 2017 Aug 11;7(1):7868
Comparison of optical coherence tomography angiographic changes after anti-vascular endothelial growth factor therapy alone or in combination with photodynamic therapy in polypoidal choroidal vasculopathy. Teo KYC, Yanagi Y, Lee SY, Yeo IYS, Tan GSW, Mathur R, Chan CM, Wong TY, Cheung CMG. Retina. 2017 Aug 1
Choroidal vascular hyperpermeability as a predictor of treatment response for polypoidal choroidal vasculopathy. Yanagi Y, Ting DSW, Ng WY, Lee SY, Mathur R, Chan CM, Yeo I, Wong TY, Cheung GCM. Retina. 2017 Jul 12
Prevalence and risk factors for nonexudative neovascularization in fellow eyes of patients with unilateral age-related macular degeneration and polypoidal choroidal vasculopathy. Yanagi Y, Mohla A, Lee WK, Lee SY, Mathur R, Chan CM, Yeo I, Wong TY, Cheung CMG. Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3488-3495
Systemic, ocular and genetic risk factors for age-related macular degeneration and polypoidal choroidal vasculopathy in Singaporeans. Cheung CM, Laude A, Yeo I, Tan SP, Fan Q, Mathur R, Lee SY, Chan CM, Tan G, Lim TH, Cheng CY, Wong TY. Sci Rep. 2017 Jan 25;7:41386
Characterization and differentiation of polypoidal choroidal vasculopathy using swept source optical coherence tomography angiography. Cheung CMG, Yanagi Y, Mohla A, Lee SY, Mathur R, Chan CM, Yeo I, Wong TY. Retina. 2017 Aug;37(8):1464-1474
HbA1c, systolic blood pressure variability and diabetic retinopathy in Asian type 2 diabetics. Foo V, Quah J, Cheung G, Tan NC, Ma Zar KL, Chan CM, Lamoureux E, Tien Yin W, Tan G, Sabanayagam C. J Diabetes. 2017 Feb;9(2):200-207
Choroidal thickness changes in age-related macular degeneration and polypoidal choroidal vasculopathy: A 12-month prospective study. Ting DS, Ng WY, Ng SR, Tan SP, Yeo IY, Mathur R, Chan CM, Tan AC, Tan GS, Wong TY, Cheung CM. Am J Ophthalmol. 2016 Apr;164:128-36
Prevalence and clinical correlates of focal choroidal excavation in eyes with age-related macular degeneration, polypoidal choroidal vasculopathy and central serous chorioretinopathy. Lim FP, Wong CW, Loh BK, Chan CM, Yeo I, Lee SY, Mathur R, Wong D, Wong TY, Cheung CM. Br J Ophthalmol. 2016 Jul;100(7):918-923. doi: 10.1136/bjophthalmol-2015-307055. Epub 2015 Oct 26
Improved specificity of polypoidal choroidal vasculopathy diagnosis using a modified Everest criteria. Cheung CM, Laude A, Wong W, Mathur R, Chan CM, Wong E, Wong D, Wong TY, Lim TH. Retina. 2015 Jul;35(7):1375-80
Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians. Cheng CY, Yamashiro K, Chen LJ, Ahn J, Huang L, Huang L, Cheung CM, Miyake M, Cackett PD, Yeo IY, Laude A, Mathur R, Pang J, Sim KS, Koh AH, Chen P, Lee SY, Wong D, Chan CM, Loh BK, Sun Y, Davila S, Nakata I, Nakanishi H, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Matsuda F, Mori K, Yoneya S, Sakurada Y, Iijima H, Iida T, Honda S, Lai TY, Tam PO, Chen H, Tang S, Ding X, Wen F, Lu F, Zhang X, Shi Y, Zhao P, Zhao B, Sang J, Gong B, Dorajoo R, Yuan JM, Koh WP, van Dam RM, Friedlander Y, Lin Y, Hibberd ML, Foo JN, Wang N, Wong CH, Tan GS, Park SJ, Bhargava M, Gopal L, Naing T, Liao J, Ong PG, Mitchell P, Zhou P, Xie X, Liang J, Mei J, Jin X, Saw SM, Ozaki M, Mizoguchi T, Kurimoto Y, Woo SJ, Chung H, Yu HG, Shin JY, Park DH, Kim IT, Chang W, Sagong M, Lee SJ, Kim HW, Lee JE, Li Y, Liu J, Teo YY, Heng CK, Lim TH, Yang SK, Song K, Vithana EN, Aung T, Bei JX, Zeng YX, Tai ES, Li XX, Yang Z, Park KH, Pang CP, Yoshimura N, Wong TY, Khor CC. Nat Commun. 2015 Mar 30;6:6817
Three-year results of polypoidal choroidal vasculopathy treated with photodynamic therapy: Retrospective Study and Systematic Review. Wong CW, Cheung CM, Mathur R, Li X, Chan CM, Yeo I, Wong E, Lee SY, Wong D, Wong TY. Retina. 2015 Aug;35(8):1577-93
New loci and coding variants confer risk for age-related macular degeneration in East Asians. Cheng CY, Yamashiro K, Chen LJ, Ahn J, Huang L, Huang L, Cheung CM, Miyake M, Cackett PD, Yeo IY, Laude A, Mathur R, Pang J, Sim KS, Koh AH, Chen P, Lee SY, Wong D, Chan CM, Loh BK, Sun Y, Davila S, Nakata I, Nakanishi H, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Matsuda F, Mori K, Yoneya S, Sakurada Y, Iijima H, Iida T, Honda S, Lai TY, Tam PO, Chen H, Tang S, Ding X, Wen F, Lu F, Zhang X, Shi Y, Zhao P, Zhao B, Sang J, Gong B, Dorajoo R, Yuan JM, Koh WP, van Dam RM, Friedlander Y, Lin Y, Hibberd ML, Foo JN, Wang N, Wong CH, Tan GS, Park SJ, Bhargava M, Gopal L, Naing T, Liao J, Ong PG, Mitchell P, Zhou P, Xie X, Liang J, Mei J, Jin X, Saw SM, Ozaki M, Mizoguchi T, Kurimoto Y, Woo SJ, Chung H, Yu HG, Shin JY, Park DH, Kim IT, Chang W, Sagong M, Lee SJ, Kim HW, Lee JE, Li Y, Liu J, Teo YY, Heng CK, Lim TH, Yang SK, Song K, Vithana EN, Aung T, Bei JX, Zeng YX, Tai ES, Li XX, Yang Z, Park KH, Pang CP, Yoshimura N, Wong TY, Khor CC. Nat Commun. 2015 Jan 28;6:6063
A prospective study of treatment patterns and 1-year outcome of Asian age-related macular degeneration and polypoidal choroidal vasculopathy. Cheung CM, Li X, Mathur R, Lee SY, Chan CM, Yeo I, Loh BK, Williams R, Wong EY, Wong D, Wong TY. PLoS One. 2014 Jun 30;9(6)
Trends in age-related macular degeneration management in Singapore. Ng WY, Cheung CM, Mathur R, Chan CM, Yeo IY, Wong E, Lee SY, Loh BK, Wong D, Wong TY. Optom Vis Sci. 2014 Aug;91(8):872-7
Argon laser with and without anti-vascular endothelial growth factor therapy for extrafoveal polypoidal choroidal vasculopathy. Gemmy Cheung CM, Yeo I, Li X, Mathur R, Lee SY, Chan CM, Wong D, Wong TY. Am J Ophthalmol. 2013 Feb;155(2): 295-30
Six-month visual prognosis in eyes with submacular haemorrhage secondary to age-related macular degeneration or polypoidal choroidal vasculopathy. Cheung CM, Bhargava M, Xiang L, Mathur R, Mun CC, Wong D, Wong TY. Graefes Arch Clin Exp Ophthalmol. 2013 Jan;251(1):19-25. doi: 10.1007/s00417-012-2029-1. Epub 2012 May 26
Identification of tear fluid biomarkers in dry eye syndrome using iTRAQ quantitative proteomics. Zhou L, Beuerman RW, Chan CM, Zhao SZ, Li XR, Yang H, Tong L, Liu S, Stern ME, Tan D. J Proteome Res. 2009 Nov;8(11):4889-905