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Clin Assoc Prof Anna Tan

Clin Assoc Prof Anna Tan

MBBS, M Med(Ophth), FRCS(Ed), FAMS

Clinician Investigator, Singapore Eye Research Institute

Research Interest:
  • ​Low vision

  • Patient reported outcomes

  • Visual rehabilitation

  • Medical Retina

  • Ocular imaging

Research Appointments

  • Clinician Investigator, Singapore Eye Research Institute

Academic Appointments

  • Clinical Associate Professor SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme

Clinical Appointments

  • Senior Consultant Medical Retina Department Singapore National Eye CentreSingapore National Eye Centre
  • Senior Consultant Cataract & Comprehensive Ophthalmology Department Singapore National Eye CentreSingapore National Eye Centre
  • Clinical Director Low Vision Service Singapore National Eye CentreSingapore National Eye Centre
  • Clinical Director Ocular Imaging Department Singapore National Eye CentreSingapore National Eye Centre
  • Clinical Director Retina Centre Singapore National Eye CentreSingapore National Eye Centre
  • Director, Global Ophthalmology (SNEC-GO) Singapore National Eye CentreSingapore National Eye Centre

Profile

Clinical Associate Professor Anna Tan graduated from the University of Melbourne in 2004 after completing her basic medical degree, and obtained first-class honours with an additional Advanced Medical Science degree conjoint with Imperial College, London. She returned to Singapore to complete her ophthalmology subspecialty training (Fellowship of the Academy of Medicine Singapore) in 2013 and obtained her Fellowship of the Royal College of Surgeons in Edinburgh in December the same year. She  completed multiple medical retina fellowships at the Singapore National Eye Centre, the Ophthalmology Department at the University of Bonn under Prof Frank Holz and the Vitreous Retina Macula New York (VRMNY) under Dr. Lawrence Yannuzzi and Dr. K Bailey Freund.
 
Clinical Associate Professor Anna Tan is an avid researcher and has authored a total of 53 peer reviewed articles, 4 editorials and 4 book chapters. She has represented SNEC at many local and international conferences with various poster and oral presentations. She has been awarded multiple grants including the Khoo Clinical Scholarship Award aimed at developing research among clinicians and recently the Academic Clinical Program Grant for Clinician Scientists. Her fellowship experience in both Germany and the USA, has allowed her to cultivate interests in multi-modal ocular imaging systems and their potential for use and application in clinical practice. Since returning from her fellowship in 2016, she has been an invited speaker to multiple international and regional conferences. In addition, she has become a key opinion leader for Zeiss and have  also been invited by various other imaging companies for speaking engagements. She has received multiple grants to further her research interests including the National Medical Council Research Scholarship to pursue her PhD in Clinical Sciences. She has also won awards such as Catalyst award in the 2020 US National Academy of Medicines Healthy Longevity Global Competition, the SingHealth “Publish” Award and also gained a spot in the Interstellar initiative. Her subspecialty research interests include age-related macular degeneration, ocular imaging, low vision, visual rehabilitation, ageing and digital technology.

Professional Appointments and Committee Memberships

  • ​Member, Macula Society (2019 – present)

  • Member, International Retinal Imaging Society (2019 – present)

  • Member, International Retinal Panel (2019 – present)

  • Member, European Society of Retinal Specialist (2019 – present)

  • Committee Member, Singapore Society of Ophthalmology (2018 – present)

  • Member, Asia-Pacific Vitreo-retinal Society (2017 – present)

  • Member, Asia-Pacific Academy of Ophthalmology (2017 – present)

  • Member, American Academy of Ophthalmology (2015 – 2016)

  • Member, Singapore Society of Ophthalmology (2014 – present)

  • Member, College of Ophthalmologists, Singapore (2014 – present)

  • Adjunct Instructor, Academic Medicine Research Institute Duke-NUS (2012 – present)

Education

  • FAMS

  • FRCS(Ed)

  • M Med(Ophth) (2010)

  • MBBS (2004)

Awards

  • Catalyst Award (2020)

  • Interstellar Initiative (2020)

  • Research Training Award, National Medical Research Council (2020)

  • SingHealth “Publish” Award (2019)

  • Next Generation Vision Award (Nomination) (2017)

  • HMDP Award (2015-2016)

  • Khoo Clinical Scholarship (2012)

  • Scholarship, Christian Blind Mission (2003)

Research Studies

  • Correlating Pathological Optical Coherence Tomography Changes in Age Related Macular Degeneration with Functional Visual Losses Measured on Microperimetry (2020 – present)

  • The Efficacy Of A Stepwise Comprehensive Patient Education Program To Improve Patients' Knowledge and Compliance rates to Intravitreal Injection Therapy (2019 – 2021)

  • IVT4me-an Interactive Application for the Purpose of Education and Engagement of Patients with Macula Disease Receiving Intravitreal Injection Treatment and their Respective Care-givers (2019 -2020)

  • SIENA: Singapore Imaging Eye Network (2018 – present)

  • Optical Coherence Tomography features of Taxane Maculopathy (2018 – present)

  • Correlating Pathological Optical Coherence Tomography Changes in Age Related Macular Degeneration with Functional Visual Losses measured on Microperimetry (2018 – 2020)

  • Management of Chronic Central Serous Chorioretinopathy (2018)

  • TAAP: Translational Asian Age Related Macular Degeneration Program (2017 – present)

  • Multimodal Imaging to Correlate Structural and Functional Outcomes of Eyes with Central Vision Loss Due to Macula Disease (2016 – 2019)

  • Evaluating the Senior EyE Rehabilitation (seer) Programme: A Hospital Based Visual Rehabilitation Programme (2016 – 2019)

  • Calcified Nodules in Retinal Drusen are Associated with Disease Progression in Age-related Macular Degeneration (2016 – 2018)

  • Validation of a Novel Micro-fluid cytokine analysis platform for aqueous and vitreous humour in normal eyes with Diabetic Retinopathy (2015 – present)

Publications

  1. Tan ACS, Yanagi Y, Cheung GCM. Comparison of Multicolor Imaging and Color Fundus Photography in the Detection of Pathological Findings in Eyes with Polypoidal Choroidal Vasculopathy. Retina. 2019 Aug 27.

  2. Tan ACS, Pilgrim MG, Fearn S, Bertazzo S, Tsolaki E, Morrell AP, Li M, Messinger JD, Dolz-Marco R, Lei J, Nittala MG, Sadda SR, Lengyel I, Freund KB, Curcio CA. Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration. Sci Transl Med. 2018 Nov 7;10(466). (Article; Published in Print)

  3. Tan ACS, Freund KB, Balaratnasingam C, Simhaee D, Yannuzzi LA. Imaging of Pigment epithelial detachments with optical coherence tomography angiography. Retina. 2018 Sep;38(9):1759-1769. (Article; Published in Print)

  4. Tan AC, Man R, Wong CW, Lee SY, Lamoureux EL, Ang M. Randomized controlled trial evaluating a novel community eye-care programme for elderly with visual impairment. Clin Exp Ophthalmol. 2018 Aug;46(6):593-599. (Article; Published in Print)

  5. Tan ACS, Freund KB, Sarraf D. Reply: Choroidal changes associated with serous macular detachment in eyes with staphyloma, dome-shaped macula or tilted disk syndrome. Retina. 2018 May;38(5):e37-e38. (Editorial Material; Published in Print)

  6. Tan ACS, Tan GS, Denniston AK, Keane PA, Ang M, Milea D, Chakravarthy U, Cheung CMG. An overview of the clinical applications of optical coherence tomography angiography. Eye (Lond). 2018 Feb;32(2):262-286. (Article; Published in Print)

  7. Tan ACS, Dansingani KK, Curcio CA, Freund KB. Author Response: The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy. Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6196. (Editorial Material; Published in Print)

  8. Tan ACS, Yzer S, Freund KB, Dansingani KK, Phasukkijwatana N, Sarraf D. Choroidal changes associated with serous macular detachment in eyes with staphyloma, dome-shaped macula or tilted disk syndrome. Retina. 2017 Aug;37(8):1544-1554. (Article; Published in Print)

  9. Tan ACS, Astroz P, Dansingani KK, Slakter JS, Yannuzzi LA, Curcio CA, Freund KB. The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy. Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):2349-2358. (Article; Published in Print)

  10. Tan AC, Yzer S, Atebara N, Marr BP, Verdijk RM, Dalm VA, Freund KB, Yannuzzi L, Missotten T. Three Cases of Erdheim-Chester Disease With Intraocular Manifestations: Imaging and Histopathology Findings of a Rare Entity. Am J Ophthalmol. 2017 Apr;176:141-147. (Article; Published in Print)

  11. Tan AC, Dansingani KK, Yannuzzi LA, Sarraf D, Freund KB. Type 3 neovascularization imaged with cross-sectional and en face optical coherence tomography angiography. Retina. 2017 Feb;37(2):234-246. (Article; Published in Print)

  12. Tan ACS, Simhaee D, Balaratnasingam C, Dansingani K, Yannuzzi L. A Perspective on the Nature and Frequency of Pigment Epithelial Detachments. Am J Ophthalmol. 2016 Dec;172:13-27. (Article; Published in Print)

  13. Tan AC, Teo K, Guan OS, Koh A. Long-term outcomes of myopic choroidal neovascularisation treated with combined ranibizumab and dexamethasone characterised by multi-modal imaging. Graefes Arch Clin Exp Ophthalmol. 2016 Oct;254(10):1881-1888. (Article; Published in Print)

  14. Tan AC, Balaratnasingam C, Yannuzzi LA. Treatment of Macular Telangiectasia Type 2 With Carotenoid Supplements Containing Meso-Zeaxanthin: A Pilot Study. Ophthalmic Surg Lasers. Imaging Retina. 2016 Jun 1;47(6):528-35. (Article; Published in Print)

  15. Tan AC, Chen L, Png R, Chia A. The diagnosis and assessment of visual function in Singaporean children with electrophysiology: 10-year results. Doc Ophthalmol. 2016 Jun;132(3):189-99. doi: 10.1007/s10633-016-9539-9. (Article; Published in Print)

  16. Tan AC, Fleckenstein M, Schmitz-Valckenberg S, Holz FG. Clinical Application of Multicolor Imaging Technology. Ophthalmologica. 2016;236(1):8-18 (Article; Published in Print)

  17. Tan AC, Farooqui S, Li X, Tan YL, Cullen J, Lim W, Leng SL, Looi A, Tow S. Ocular manifestations and the clinical course of carotid cavernous sinus fistulas in Asian patients. Orbit 2014; 33(1):45-51 (Article; Published in Print)

  18. Tan AC, Tay WT, Zheng YF, Tan AG, Wang JJ, Mitchell P, Wong TY, Lamoureux EL. The impact of bilateral or unilateral cataract surgery on visual functioning:when does second eye cataract surgery benefit patients? Br J Ophthalmol. 2012; 96(6):846-851 (Article; Published in Print)

  19. Tan AC, Wang JJ, Lamoureux E, Wong WL, Mitchell P, Li JL, Tan AGT, Wong TY. Cataract prevalence varies substantially with assessment systems: comparison of clinical and photographic grading in a population-based study. Ophthalmic Epidemiol 2011; 18(4):164-170 (Article; Published in Print)

  20. Tan AC, Loon SC, Choi H, Thean L. Lens Opacities Classification System III: cataract grading variability between junior and senior staff at a Singapore hospital. J Cataract and Refractive Surgery 2008; 34(11):1948-1952 (Article; Published in Print)